Biomedical engineering
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What is Biomedical Engineering?
Using engineering mindset and skills to solve medical challenges. Example. Second Example. Your future may involve the development of: presthesis, robotics, chemical signaling, diagnosis machinery, rehabilitative equipment, software to run medical machines, drug therapies, modeling body systems and function Average salary: 92K/year |
General Background knowledge targeted at EOC prep
Standards
HE.912.C.1.3 Evaluate how environment and personal health are interrelated.
SC.912.L.16.12 Describe how basic DNA technology (restriction digestion by endonucleases, gel electrophoresis, polymerase chain reaction, ligation, and transformation) is used to construct recombinant DNA molecules (DNA cloning).
HE.912.C.1.5 Analyze strategies for prevention, detection, and treatment of communicable and chronic diseases.
SC.912.L.14.36 Describe the factors affecting blood flow through the cardiovascular system.
SC.912.L.14.52 Explain the basic functions of the human immune system, including specific and nonspecific immune response, vaccines, and antibiotics.
SC.912.L.14.26 Identify the major parts of the brain on diagrams or models.
SC.912.L.14.27 Identify the functions of the major parts of the brain, including the meninges, medulla, pons, midbrain, hypothalamus, thalamus, cerebellum and cerebrum.
SC.912.L.16.13 Describe the basic anatomy and physiology of the human reproductive system. Describe the process of human development from fertilization to birth and major changes that occur in each trimester of pregnancy.
HE.912.C.1.3 Evaluate how environment and personal health are interrelated.
SC.912.L.16.12 Describe how basic DNA technology (restriction digestion by endonucleases, gel electrophoresis, polymerase chain reaction, ligation, and transformation) is used to construct recombinant DNA molecules (DNA cloning).
HE.912.C.1.5 Analyze strategies for prevention, detection, and treatment of communicable and chronic diseases.
SC.912.L.14.36 Describe the factors affecting blood flow through the cardiovascular system.
SC.912.L.14.52 Explain the basic functions of the human immune system, including specific and nonspecific immune response, vaccines, and antibiotics.
SC.912.L.14.26 Identify the major parts of the brain on diagrams or models.
SC.912.L.14.27 Identify the functions of the major parts of the brain, including the meninges, medulla, pons, midbrain, hypothalamus, thalamus, cerebellum and cerebrum.
SC.912.L.16.13 Describe the basic anatomy and physiology of the human reproductive system. Describe the process of human development from fertilization to birth and major changes that occur in each trimester of pregnancy.
Topic 1: DNA technology and disease
Day 1-2
Objective: TSW analyze personal health and DNA Technology using digital resources.
1. Do Now: Read this article then IYB record how the 5 determinants mentioned impact personal health. After, state your opinion of the American Government's role in improving overall American health.
2. With your group discuss this webpage then decide which factor you feel is the most important. Record your answer on your group's board space
3. Read this research on our economy and personal health and discuss your personal opinion with your STEM team.
4. HIV lab purchased here. Swap with 5 students. Every time you swap, ask a fun fact about that student's life. Track via phylogeny.
4. Your team is assigned the following DNA technology:
A-restriction digestion by endonucleases
B- gel electrophoresis
C- polymerase chain reaction
D- ligation
E & F- transformation
You will research how your tech is used to construct recombinant DNA molecules (DNA cloning) then paste your answer here for Mrs. W and here for Mr. E.
5. Your team will choose one chronic disease and one communicable disease from this list or using your own research and will be presenting a general overview and A) prevention, B) detection, and C) treatment options for the disease using media of your choice.
6. HW: Gizmo: Dye Elimination with SES and Quiz
Objective: TSW analyze personal health and DNA Technology using digital resources.
1. Do Now: Read this article then IYB record how the 5 determinants mentioned impact personal health. After, state your opinion of the American Government's role in improving overall American health.
2. With your group discuss this webpage then decide which factor you feel is the most important. Record your answer on your group's board space
3. Read this research on our economy and personal health and discuss your personal opinion with your STEM team.
4. HIV lab purchased here. Swap with 5 students. Every time you swap, ask a fun fact about that student's life. Track via phylogeny.
4. Your team is assigned the following DNA technology:
A-restriction digestion by endonucleases
B- gel electrophoresis
C- polymerase chain reaction
D- ligation
E & F- transformation
You will research how your tech is used to construct recombinant DNA molecules (DNA cloning) then paste your answer here for Mrs. W and here for Mr. E.
5. Your team will choose one chronic disease and one communicable disease from this list or using your own research and will be presenting a general overview and A) prevention, B) detection, and C) treatment options for the disease using media of your choice.
6. HW: Gizmo: Dye Elimination with SES and Quiz
topic 2: bloodBloodDAY 3-4
TSW analyze blood flow using digital resources and a lab. 1. Do Now: read this article on heart disease then record IYB 3 facts you learned. Do Now 2: IYB A. draw a diagram of the relationship between blood flow through the heart and your lungs. B. Define: erythrocytes, leukocytes, pulmonary 2. Heart video 1. Video on heart health. Video on blood flow. Video on blood characteristics. Example of blood flow presentation college level-click first link
3. Differentiate: capillary, vein, artery, heart. Then make your own fake blood artery and text flow using water, creamy peanut butter, red, blue, and green food dye, corn syrup, chocolate syrup, corn starch, ,plastic cups, straws and plastic spoons Compare the viscosity of your blood with your STEM teammates' blood. Vote on which blood you would want and be able to defend your answer. Then create blocks in your arteries and test which blood is better at flowing through the blocks. Use your observations to determine the importance of blood thinners for cardiology patients. 4. Using sidewalk chalk, pick a sidewalk around campus and draw an anatomically correct heart and model blood flow through this heart. 5. Design a lab to test the effects of a stress (music, exercise, visual stimulation, etc) on heart rate. You will be turning in ONE formal lab report per group. 4. Blood Flow Practice 5. HW: Gizmo: Circulatory System with SES and quiz |
topic 3: immuneImmune systemDay 5
TSW evaluate the components of the immune system using illustrations and 3D design. 1. Do Now: Read this webpage then illustrate IYB the formation of blood cells in the bone marrow. Label all your illustration. 2. Teacher Led Instruction: Immune System Video Intro Immune System Video 2 Understand the concepts: Video 3 Video 4 3. 3D design part of your immune system, print design, then provide an explanation. 4. Differentiate IYB: Innate and Adaptive Immune System 3. Overview of Immune System: extra resource
HW: Bring in an item for someone else to blindfolded taste, an item to put in a mystery box to touch, and a mystery item to smell.
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Topic 4: brainHuman BrainDay 6
TSW evaluate the human brain using articles and a lab. 1. Do Now: A. IYB record the 5 most interesting facts from your table's allotted section: A. Physical Attributes and/or Fun and Interesting Facts B. The Developing Brain and/or Famous Brains C. Brain Function and/or Moments in History D. Psychology of the Brain E. Memory F. Dreams and Sleep B. Share one fact per member with 5 members, each from a different table. Ex: If I am table A, I share a different fact with one person from table B, C, D, E, and F. C. Recall class activity 3. Read this then research the most novice brain scan technology then post your findings including a picture here. You will be sharing with a classmate.
4. Mystery Activity: Taste, Touch, Smell activity. Research which parts of your brain were at work. Record a diagram of the parts of the brain you used. Post here for Mrs. W and here for Mr. E.
Draw or model, label, and provide function for the following brain parts: cerebrum, cerebellum, pons, medulla oblongata, brain stem, frontal lobe, parietal lobe, occipital lobe, and temporal lobe; meninges, medulla, midbrain, hypothalamus, thalamus,
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Challenge From Biomedical Enginner Jason Ghannadian: Post answer here.
I have 2 good questions. They are not necessarily as "cool" as the multimillion dollar prosthetic limbs, but the problems are way more important to amputees and it would be interesting to see what high school students come up with.
1) Even with revolutionary advances in prosthetics technology, many amputees choose to only wear their prosthesis for a few years after amputation and then they will suddenly abandon the device. The number one reason for abandonment in lower extremity amputees is comfort. The problem has to do with the socket which attaches the device to the amputee's residual limb. The socket is an airtight attachment which covers a good portion of the skin, and the skin sweats (think wearing rubber boots or lab gloves all day.) Eventually the skin breaks down causing blisters and even bleeding. Once the skin is damaged the person must wait for their leg to heal before wearing their prosthesis again. After years of this vicious cycle most amputees find a wheelchair is easier to use. Once the patient is in a wheelchair their life expectancy decreases dramatically due to other problems (pressure sores from sitting, Type II diabetes, problems with digestion, etc - Google search 'why sitting is killing you' for more info.) To date a lot of research has resulted in little advancement on ways to combat this problem. How would you solve it?
This one might be a little more difficult, but could still yield some interesting solutions.
2) Every unilateral (one side) lower extremity amputee relies on the stability of the biological leg they still have to get around. The problem is 10 years post amputation every amputee has arthritis in their biological knee with more than 50% of them needing knee surgery during that period. Understand that every amputee removes their prosthetic leg during resting/sleeping and if they need to get up quickly (to use the restroom for instance) many of them hop if they are able because putting on the leg is time consuming and an annoyance. It's likely difficult to change this pattern of behavior or to intervene with some sort of technology (ex. crutches next to the bed for nighttime restroom trips etc.) How would you save (or slow degeneration of) their sound knee during their other ADLs (activities of daily living.)
Each one of these problems has had millions of research dollars spent on them, and we are not really close to a solution
Jason Ghannadian
I have 2 good questions. They are not necessarily as "cool" as the multimillion dollar prosthetic limbs, but the problems are way more important to amputees and it would be interesting to see what high school students come up with.
1) Even with revolutionary advances in prosthetics technology, many amputees choose to only wear their prosthesis for a few years after amputation and then they will suddenly abandon the device. The number one reason for abandonment in lower extremity amputees is comfort. The problem has to do with the socket which attaches the device to the amputee's residual limb. The socket is an airtight attachment which covers a good portion of the skin, and the skin sweats (think wearing rubber boots or lab gloves all day.) Eventually the skin breaks down causing blisters and even bleeding. Once the skin is damaged the person must wait for their leg to heal before wearing their prosthesis again. After years of this vicious cycle most amputees find a wheelchair is easier to use. Once the patient is in a wheelchair their life expectancy decreases dramatically due to other problems (pressure sores from sitting, Type II diabetes, problems with digestion, etc - Google search 'why sitting is killing you' for more info.) To date a lot of research has resulted in little advancement on ways to combat this problem. How would you solve it?
This one might be a little more difficult, but could still yield some interesting solutions.
2) Every unilateral (one side) lower extremity amputee relies on the stability of the biological leg they still have to get around. The problem is 10 years post amputation every amputee has arthritis in their biological knee with more than 50% of them needing knee surgery during that period. Understand that every amputee removes their prosthetic leg during resting/sleeping and if they need to get up quickly (to use the restroom for instance) many of them hop if they are able because putting on the leg is time consuming and an annoyance. It's likely difficult to change this pattern of behavior or to intervene with some sort of technology (ex. crutches next to the bed for nighttime restroom trips etc.) How would you save (or slow degeneration of) their sound knee during their other ADLs (activities of daily living.)
Each one of these problems has had millions of research dollars spent on them, and we are not really close to a solution
Jason Ghannadian
topic 5: reproduction
The human REPRODUCTIVE system
Objective: TSW explore human reproduction using a project.
1. Do Now: Watch this Video on 3D printing sonogram for blind mother. Discuss the implications behind this use of technology with your team.
2. Male and Female reproductive organs: Teacher Led Instruction
2. You will create a lesson with your team addressing the standard: Describe the basic anatomy and physiology of the human reproductive system. Describe the process of human development from fertilization to birth and major changes that occur in each trimester of pregnancy.
Address:
1. Why are hormones essential to puberty and reproduction in both males and females?
2. Evaluate the three trimesters of pregnancy.
3. Analyze how the following contribute to fetal development : placenta, umbilical cord, amniotic sac, and amniotic fluid.
4. Solve this problem: A working pregnant mother is experiencing extreme fatigue. As a result, the quality of her work is suffering. She is a Biomedical Engineer currently designing a synthetic uterus. What do you suggest she do?
Rubric
1. Do Now: Watch this Video on 3D printing sonogram for blind mother. Discuss the implications behind this use of technology with your team.
2. Male and Female reproductive organs: Teacher Led Instruction
2. You will create a lesson with your team addressing the standard: Describe the basic anatomy and physiology of the human reproductive system. Describe the process of human development from fertilization to birth and major changes that occur in each trimester of pregnancy.
Address:
1. Why are hormones essential to puberty and reproduction in both males and females?
2. Evaluate the three trimesters of pregnancy.
3. Analyze how the following contribute to fetal development : placenta, umbilical cord, amniotic sac, and amniotic fluid.
4. Solve this problem: A working pregnant mother is experiencing extreme fatigue. As a result, the quality of her work is suffering. She is a Biomedical Engineer currently designing a synthetic uterus. What do you suggest she do?
Rubric